What Part Do My T-cells Play In My Immune System
What Part Do My T-cells Play In My Immune System, the immune system has two parts innate and adaptive the innate is the first to detect when an organism does not belong to the body and directs the adaptive part to tackle the intruder.
When a kidney transplant takes place a specialized subtype of white cells that are part of the innate immune system called dendritic cells carry information from the kidney to the local white nodes called lymph nodes.
Through blood circulation in the lymph node cells of the adaptive immune system called t-cells continually circulate between the blood and lymph nodes and are on constant alert for any sign that the body is under attack.
Within the t-cells a small subpopulation called regulatory t-cells control how the immune system will react to intruders dendritic cells which are coming from the transplanted kidney enter the lymph node and begin to mix with the t-cells.
And as they come into contact with the t-cells some T cells become activated the body’s defense mechanism has been triggered the activated T cells called effector T cells start to multiply and go to the kidney.
And a tacit information displayed by the dendritic cells have told the T cells where the intruder can be found they use the vessels of the body to travel their T cells attack the kidney and attempt to destroy it as quickly as possible.
The immune system is very powerful against foreign intruders if the immune system is not controlled the effector T cells attack any unknown organism they find in the body so if a virus enters the body the T cells would be alerted to its presence by dendritic cells different T cells from those attacking the kidney will attack and destroy the virus infected cells.
The current protocol to control the immune system during a transplant is the use of immunosuppressive drugs these drugs suppress the immune system paralyzing it from attacking the transplant at first the t-cells detect the foreign organ and still try to attack it but the immunosuppressive drugs prevent this from happening before any significant damage has been done.
However here lies the problem the whole immune system is paralyzed by the immunosuppressive drugs so if a virus were to be introduced the immune system cannot react to it and the person becomes ill to prevent organ rejection.
The patient must take immunosuppressive drugs for the life of the transplant with a paralyzed immune system infections are a constant threat .
The team at King’s College London have developed a way to harness the power of the immune system whilst maintaining the body’s capacity to resist infectious diseases a large sample of blood is taken from the recipient of an organ before the transplant has taken place.
From within this collection of cells a small subpopulation of t-cells known as the regulatory t-cells are extracted these cells are responsible for regulating the immune response and decide when and what effector T cells are permitted to attack.
These cells are separated selected for specificity and multiplied in their Millions outside of the body in a flask in a sterile environment after a few weeks and just after the transplant takes place these regulatory t-cells are concentrated and injected back into the body.
When dendritic cells from the new kidney enter the lymph node the T effectors specific for the transplant will be inhibited from attacking the kidney by the injected regulatory t-cells.
But other T cells specific for the viruses retain their ability to fight infection when a virus enters the body the immune system is alerted to the danger and destroys them.
Ssuch a technique allows the patient to retain the transplant for their entire life free from immunosuppressive drugs and therefore free from drug related diseases such as infections.
Stock piling or good T-Cells and growing more for reinjecting them back into our bodies when an attack is imminent may be something all will be doing in the future if viruses like the coronavirus become more prevelant.
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Doctor Silverstone Interview Cont… “The Gut”
I do not want to take a PPI because I am a firm believer that part of your general immunity does come from the gut.
I do not believe in the leaky gut concept. Serotonin initial production is in the gut. Food consumption plays a major role. I did not want to take a PPI to disturb anything.
In addition, we formulated our digestion & immunity formula, which has ginger in it and it has turmeric, again, an anti-inflammatory and l-glutamine, which has shown to be good as a natural way to prevent reflux.
l-glutamine, which has shown to be good as a natural way to prevent reflux.Doctor Silverstone
Again, added the multivitamin Bs with the exception of B6, which by the way could kick up the reflux.
So people who are taking multiple vitamins, again, this is where literature is important, It shows that it could actually trigger reflux. Therefore, we remove that one out of the entire cascade of ingredients..